Global nanocapsules market is anticipated to grow over the forecast period on account of its upcoming and increasing demand in the pharmaceutical and food and beverage industry. Nanocapsules are colloids which have their particle dimensions measured in nanometers such as emulsion of oil and water or biological lipids. They have their applications for drug delivery, cosmetics, food enhancement, self-healing of materials and for nutraceuticals. Researchers from the Biotechnology & Food Engineering Department at the Israeli Institute of Technology, created nanocapsules few years back, based on the natural food components. These natural food components have vitamins and health-enhancing nutrients trapped in them which usually don’t dissolve properly in liquids. Nanocapsules can thus be added to drinks for protecting the nutrients inside them impacting the richness of food and beverage industry globally.
The application process of nanocapsules involves a famous technology which is used currently worldwide, termed as layer-by-layer (LBL). Layer-by-layer technology constitutes several tools for making nano and micro-sized capsules having their advantages in pharmaceutical and non-pharmaceutical industries. They are widely used in this technology for the development of variety of advanced drug-delivery products, food ingredients, nutraceuticals, foodstuffs, diagnostics, biosensors, enzyme catalysts, paper and paints. LBL comprises a set of encapsulation methods developed by a group of scientists at the Max-Planck-Institute of Colloids and Interfaces (Germany). During its process, capsules are built layer-wise in a series of steps with each step characterized by the consolidation of polyelectrolyte molecules which form an ultra-thin layer of polymer. A polyelectrolyte is now selected for each layer for bearing the opposite charge of its previous layer. The electrostatic interaction between the consolidated polymers forms highly dense capsule shells at the last. Companies such as Capsulution Nanoscience AG, use this technology for its various other end uses, including its usage for non-invasive blood sugar measurement, and for protection and stabilization of low-soluble drug substances.
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Nanocapsules were used in a recent research study conducted by UCLA Samueli school of engineering and applied science. The research was based on developing a new delivery platform inside a cell that uses nanocapsules. Nanocapsules can be monitored according to their cellular environment owing to their attributes of having thin polymer shells and protein-core. Clinicians follow a method which involves sending healthy proteins directly inside the human cells by replacing the malfunctioning ones. It is the most safe and direct approach to treat diseases. Usually during this process the cells get broken down frequently or are digested by enzymes before they reach their target. This adversely affects the process by lowering down its delivery efficiency. Researchers at ULCA have carved out a new method to deliver proteins efficiently and effectively by the use of nanocapsules. Microscopic containers of nanocapsules have the capacity to carry the protein cells effectively without letting them get degraded. Nanocapsule containers allow the embedded protein inside it to travel safely to the nearby cells before they interact with the molecular substrates The nanocapsule membrane carrying protein remain intact or degrade depending on the size of substrates it comes in contact with.
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